Paracetamol Reduce Effectiveness of Vaccines

The parents should not have to panic too much if the child a fever after being immunized. Fever is a normal thing and not a disease. Provision of fever-lowering drugs such as paracetamol can actually reduce the effectiveness of the vaccine.

Fever after immunization is normal and a sign the body is formed "armies" of antibodies that will provide protection for children from disease. Dr.Robert according to T. Chen, blood safety specialists from the Center for Disease Control and Prevention, the United States.

"Unless children suffering from high fever and doctors specifically recommend it, should not have to use fever-lowering drugs after vaccination, especially if the reason to prevent the fever," said Chen.

The researchers, headed by the University Dr.Roman Prymula of Defense Czech Republic, trying to find out the effect of paracetamol against vaccination. Who have received vaccines including Hib, diphtheria, tetanus, whooping cough, hepatitis B, polio, and rotavirus (diarrhea).

The researchers conducted two studies. The first is when a baby receives the first and second vaccination when they receive further vaccination. Object of this study was 459 infants and toddlers who randomly asked to receive paracetamol every six to eight hours within 24 hours after being immunized. The second is the child does not get paracetamol.

The researchers found that babies given paracetamol is a bit of a fever, but the system produced antibodies are also low. Likely that anti-inflammatory activity of the substance contained in the fever-lowering drugs lead to interference with the system so that antibodies produced antibodies is low.

"Unless there is special reason to control the fever, such as a history of seizures, with fever, fever-lowering drugs should not routinely given after the immunization," said Chen.

An infectious disease specialist, Dr. Siegel March from New York University School of Medicine, USA, said that the fever-lowering drugs will reduce the antibody response is reasonable. Moreover, the immune system response is the inflammatory response. "If a child is ill, overcome the pain. But if the child high fever, you should immediately lower the fever with fever-lowering drugs," he said.